Depression: Improving Recruitment into Clinical Trials

Embedding research in clinical services is a core function of the NHS. National policy states that any eligible patient will be offered the opportunity to participate in clinical research. Currently, patients with depression do not get this chance. Most trials recruit less than 10% of eligible participants and only 30% of trials for depression recruit to target and on time.

DiReCT is developing and testing a new systematic recruitment method for participants with depression into clinical research, including observational studies and randomized controlled trials (RCT’s) of psychological treatments – the ‘Cohort Multiple RCT’ (cmRCT) system.

DiReCT will use the cmRCT method to establish a longitudinal cohort of patients with depression using a research recruitment method which is closely aligned to the way treatments are offered to patients in routine clinical practice.



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