COBRA

A Randomised Controlled Trial of Behavioural Activation vs. Cognitive Behavioural Therapy for depression

Project Overview

Clinical depression is one of the most common and debilitating of the psychiatric disorders. It accounts for the greatest burden of disease among all mental health problems, and is expected to become the second-highest amongst all general health problems by 2020.

COBRA is a Randomised Controlled Trial comparing the clinical and cost effectiveness of Behavioural Activation (BA) vs. Cognitive Behavioural Therapy (CBT) for depression. Patients with depression will be recruited from primary care, and will be randomised to receive either BA or CBT from a trained therapist. We will measure clinical outcomes before and 6, 12 and 18 months after therapy. We will also be comparing the cost effectiveness of the two therapies.

Register Interest Project Abstract

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